Thank you for contacting Telerik support team. I logged a PITS issue regarding the problem that you experience. Its ID is 8871. You can follow it using this URL and vote for it:
There isn't a way to globally disable creating of additional URL in 4.3. As for images, you can try to unpublish your images, make changes while building your site and publish them before going live. Making changes in unpublished images will not add additional URLs. As for the URLs to pages from your project that are not recalculated, this is an expected behaviour and these URLs that are already created with RadEditor should be changed manually.